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folding
Protein folding is the physical process by which a protein chain acquires its native 3-dimensional structure, a conformation that is usually biologically functional, in an expeditious and reproducible manner. It is the physical process by which a polypeptide folds into its characteristic and functional three-dimensional structure from random coil.
Each protein exists as an unfolded polypeptide or random coil when translated from a sequence of mRNA to a linear chain of amino acids. This polypeptide lacks any stable (long-lasting) three-dimensional structure (the left hand side of the first figure). As the polypeptide chain is being synthesized by a ribosome, the linear chain begins to fold into its three-dimensional structure. Folding begins to occur even during translation of the polypeptide chain. Amino acids interact with each other to produce a well-defined three-dimensional structure, the folded protein (the right hand side of the figure), known as the native state. The resulting three-dimensional structure is determined by the amino acid sequence or primary structure (Anfinsen's dogma).The correct three-dimensional structure is essential to function, although some parts of functional proteins may remain unfolded, so that protein dynamics is important. Failure to fold into native structure generally produces inactive proteins, but in some instances misfolded proteins have modified or toxic functionality. Several neurodegenerative and other diseases are believed to result from the accumulation of amyloid fibrils formed by misfolded proteins. Many allergies are caused by incorrect folding of some proteins, because the immune system does not produce antibodies for certain protein structures.Denaturation of proteins is a process of transition from the folded to the unfolded state. It happens in cooking, in burns, in proteinopathies, and in other contexts.
The duration of the folding process varies dramatically depending on the protein of interest. When studied outside the cell, the slowest folding proteins require many minutes or hours to fold primarily due to proline isomerization, and must pass through a number of intermediate states, like checkpoints, before the process is complete. On the other hand, very small single-domain proteins with lengths of up to a hundred amino acids typically fold in a single step. Time scales of milliseconds are the norm and the very fastest known protein folding reactions are complete within a few microseconds.
This uses a really solid locking mech which is really easy to use. It is new and cost $130 new plus another $15 for the rubber buttpad that actually has a bit of cushion to it. I have 2 of these at $100 each
https://agparms.com/agp-arms-ar-15-folding-stock/
TRADES WANTED SEE BELOW
TRADES...
New old stock. Scarce Russian AK100-series buttstock, for a 5.5mm folding trunnion. Made at Izhmash. Does not have the Izzy logo.
Long shot, but looking to trade for the older version of this stock, without the cutout for strap. Last photo is what I'm looking for. Will also purchase it from you...
These don't come up often. Neat old folding shotgun. Does need some stock work, but functions as it should. I was going to fix it up, but never got around to it.
$200
TRADES:
Romak
RPK
5.45x39 AK
Cash on my end
*Can is not included
Like new original owner
KNS adjustable gas piston
-Factory spec-
Caliber: 7.62x39
Barrel Length: 10.5"
Barrel Twist Rate: 1:9.5
Barrel Material: 4150 Steel
Barrel Finish: Gas Nitride
Muzzle Device: Mini Krink Brake
Muzzle...
For sale is a Cold Steel SRK in CPM 3V. It comes with the sheath pictured. It's brand new and has never been used or carried. Was going to use this for a bug out bag, but went with something else instead. I also have 2 Buck 110 LT Folding Hunters. One is brand new in package and the other is...
Up for sale, Southwest Washington, Vancouver area, Clark county area.
OEM Ruger (Made by Samson) folding stock for Mini-14 Mini-30. Blued steel and wood.
Fits any mini 14 Series 181 to current 580 +.
I had always wanted one of these. They are always on backorder. (Retails for $310) I had...
FS: CNC Warrior AKM Pattern Folding Stock ($140): Galil-style tubular aluminum folding stock for AKM-pattern rifles & shotguns. "Pretty minty" with round count in the 10s. Comes with Smokie's Leather "bakelite" wrap, spare needle & thread, all hardware. NATO length (9"), right side folding.
FTF...
WTB/trade for a decent middle of the road set BUIS in blk. Something like a fixed Midwest Industries Combat set or just a fixed front Combat sight. I need at least a fixed front Midwest Ind BUIS to complete one set. Used and rode dirty I don't care.
Also interested in spare 5.56 NiB/chrome bolt...
Brand new KAC 600m rear sight
This sight is still in sealed blister pack.
I take PayPal friends and family/Venmo
Shipping OK, S/H free
No trade requests please.
No separate part sales please
No face-to-face sales requests please
I’m looking to buy a Kriss vector in
( 9mm carbine ) not the pistol with the folding stock not the AR collapsible stock also id rather buy it used as to keep my cost down but if it’s under the retail price that would be great.any extras are a plus.
I may be open to a vector 9 mm pistol for the...
Classic Army brand (airsoft) folding stock used in good condition. I only used the adapter with an SB tactical SBT brace. Fit good with my GSG 522pk and SB brace didn't have to do any mod
2 new GSG mags
$60
Does not come with the SB brace
https://www.sb-tactical.com/product/sbt/
Meet near SE...
Never even had a chance to fire it
Brand new in the box
CZ cleaning kit
Timmy trigger
Two 20 round mags
V6 compensator
HBI extended charging handlHBI selector switches
26" barrel
Will include factory trigger
I do have some 30 round mags available to be sold separately